Misty: his devoted stalker; least sensational of the Sensational Sisters
Brock: a lonely virgin who dreams of breeding—Pokémon; third-wheel to Ash and Misty
Our "Villains" (the real heroes)
Meowth: a feline Pokémon gifted by the gods with the singular ability to talk to humans; he dreams of sitting on Giovanni's lap
Jessie: the most beautiful woman on the planet gifted by the gods with the singular ability to be the most beautiful woman on the planet
James: her effete best friend; he dreams of being the most beautiful woman on the planet (and possibly also sitting on Giovanni's lap)
Residing in Pallet Town
Samuel Oak: a first-rate Pokémon Professor and even-firster-rate horny old man; Ash's probable father
Delia Ketchum: his paramour; Ash's mother
Gary Oak: the world's greatest Pokémon trainer; Ash's older nephew
Others
Giovanni: leader of the criminal organization Team Rocket; he is seeking the world's most powerful Pokémon
Nurses Jenny: an extended family of identical veterinarians; they dispense free Pokémon healthcare services on behalf of the benevolent Kantonian Stalinist state
Officers Jenny: an extended family of identical authoritarians; they exercise the monopoly on violence on behalf of the malevolent Kantonian Stalinist state